Tsev > Xov xwm > Ntsiab lus
Txoj Cai Thiab Txoj Kev Nyab Xeeb Ntawm Cov Tshuaj Noj
- Mar 28, 2018 -

Kev pom zoo ntawm kev hnyav hnyav dua tshiab yuav tsum ua raws nraim rau kev ua tau zoo thiab kev nyab xeeb ib txhij. Raws li cov kev xav tshuaj, cov tshuaj teev cov tshuaj poob ceeb thawj tau ua raws li FDA cov txiaj ntsim kev soj ntsuam cov txiaj ntsim rau cov yeeb yuj phaus: (1) Cov tshuaj tsis zoo thiab cov placebo tom qab 1 xyoo, 2 pawg neeg koom nrog qhov kev poob phaus yuav tsum tsis pub tsawg tshaj 5%. (2) Feem ntau ntawm cov kev kawm nrog 5% lossis ntau tshaj qhov hnyav ntawm pawg neeg tshuaj kho mob tsis tsawg dua 35%, thiab qhov kev faib yuav tsum yog ob zaug ntawm pawg placebo. Tab sis qhov hnyav-poob tshuaj nyob rau hauv kev kho mob ntawm lub cev poob zoo thaum tib lub sijhawm, muaj teeb meem loj txog kev ruaj ntseg. Ib qho tseem ceeb tshaj plaws yog qhov qab los noj mov hauv lub plhaw (amphetamine) (fenfluramine) thiab Amphetamine (phentermine), uas tau siv ntau xyoo 1990s vim kev noj zaub mov tsis zoo, tab sis raug yuam tawm ntawm kev ua lag luam vim ntsig txoj hlab ntsig thiab plawv plawv. Lwm cov tshuaj zoo li amphetamine thiab quas-sympathetic kuj muaj kev txaus ntshai ntawm kev quav tshuaj, kev mob toxicity thiab kev cia siab tuag. Lub neej thooj plawv ntawm mob ntsig txog mob ntsws los ntawm Amire (Aminorex) yog 50%. Amphetamine-amine (phenylpro-panolamine) tuaj yeem ua rau cov hlab ntaws thiab hlab ntsha tawg. Ephedrine (ephedrine) ua rau mob plawv, ntshav siab, palpitation, mob hlab ntsha tawg thiab tuag taus. Sibutramine sibutramine (sibutramine) tuaj yeem ua rau muaj kab mob ntxiv.

Rimonabant (rimonabant) yog ib hom kab mob hu ua cannabis receptor CBL antagonist uas tuaj yeem ua rau muaj kev nyuaj siab thiab tua tus kheej. Cov tshuaj no yuav raug rho tawm ntawm lub khw. Tam sim no, tseem muaj 5 hom kev siv tshuaj rau kev siv tshuaj kho mob, xws li 1999 tau pom zoo Orlistat (ORLISTAT) Capsules, Green Kaslin (Lorcaserin) thiab amphetamine thiab topiramate (Qsymia) qeeb tso tshuaj tshuaj tso cai hauv xyoo 2012, thiab 2014 tau pom zoo los ntawm hydrochloride thiab Ketamine hydrochloride compound tau tso tawm cov ntsiav tshuaj (Contrave) thiab liraglutide peptide (liraglutide) txhaj.


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